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Propargyl-Gly(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG4)-MMAE Size:5mg Sci Transl Med 2021

SKU 50659747579
4.4
EUR495.00 EUR544.00

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Description

Sci Transl Med 2021

436 SMILES OC(=O)CCCCCCNC1=C2CN(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Product Name DOTA-tris(t-Bu)ester-PEG6 Synonyms CAS Number n/a Related CAS Molecular Formula C40H77N5O13 Molecular Weight 836

in particular

enabling kinetic measurements

Propargyl-Gly(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG4)-MMAE Size:5mg Sci Transl Med 2021SOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. In this product, a Propargyl Gly(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The propargyl functional group is widely employed in click chemistry to undergo selective cycloaddition with azides. Additionally, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous

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